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Past Clinical Trials

 

What osteoarthritis treatment is best for you?  (06/11/2015)

 

If you have knee and/or hip osteoarthritis (OA), the process of deciding on a treatment can be difficult.

 

The University of Sydney is conducting reserach to see what helps people with hip or knee OA by conducting a research project on decision aids.

A 'decision aid' is a tool to help you understand what your treatment options are and what is important to you in deciding among the various options.

The main purpose of this study is to evaluate the usefulness of the decision aid for people with osteoarthritis and to see if there is a change in the quality of decisions after using having used it. 

 

Read more and do the survey here: http://healthbook.health.usyd.edu.au/index.php?PageID=survey_respond&SurveyID=1143

Allow about 30 minutes to complete the survey and to find out what OA treatments are best for you.

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CUBA – Cane for Knee Pain Study  (02/11/2015)

  • Are you 50 years of age or older?

  • Do you have persistent knee pain on most days of the month?
  • Would you be willing to start using a cane daily for 12 weeks?

Then the CUBA – Cane for Knee Pain Study may be for you. The University of Melbourne (Parkville) and Royal North Shore Hospital Sydney (St Leonards) are investigating the effect of daily walking with a cane for 12 weeks on knee osteoarthritis, pain and physical function.

If you are interested in participating or would like more information, please visit the study website http://cubastudy.info or contact Charlotte on:

Phone: 03 8344 0485 

Email:   This email address is being protected from spambots. You need JavaScript enabled to view it.

 

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Do you suffer from fibromyalgia? (22/7/15)

The Monash Alfred Psychiatry Research Centre (MAPrc) at the Alfred Hospital campus is currently seeking volunteers for a clinical trial of a non-medication investigational treatment for fibromyalgia called repetitive Transcranial Magnetic Stimulation (rTMS).

rTMS is a painless, safe, and non-invasive means of stimulating nerve cells in the brain. We are conducting this study to see whether we can reduce the symptoms associated with fibromyalgia.

Participants should be located in Melbourne and be:

  • between 18-65 years old
  • have a diagnosis of fibromyalgia

Participation will involve attending MAPrc for 20 rTMS treatments over a four week period. Each treatment takes approximately 30 minutes.

For more information click here or contact Dr Bernadette Fitzgibbon:

Phone:   03 9076 9860

Email:     This email address is being protected from spambots. You need JavaScript enabled to view it.
 

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STEP Trial - Safety, Tolerability and Efficacy of Progenza for osteoarthritis (21/7/15)

The STEP trial is a randomised phase 1 clinical trial, investigating the safety and efficacy of a stem cell therapy (Progenza) for knee osteoarthritis. It will compare stem cells to placebo, looking at safety, pain, function and cartilage loss in participants.

Study participants need to be located in Sydney and be:

  • between 40-65 years old
  • have moderate to severe knee pain associated with osteoarthritis

For more information click here or contact Carolyn:

Phone:   0434 292 110

Email:      This email address is being protected from spambots. You need JavaScript enabled to view it.

 

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Melbourne - Knee Osteoarthritis Pain study  (17/7/2015)

This study is a randomised clinical trial, investigating a new medication for knee pain in adults with osteoarthritis. We will compare amitriptyline 25mg tablets with a placebo, looking at knee-pain and its effect on daily life over a 12-week period. If effective, this medication will offer a new way to manage pain for people with knee osteoarthritis.

Participants should be located in Melbourne and be:

  • between 40-70 years old
  • have knee pain

For more information contact Cameron, Molly, or Clare:

Phone:    03 9903 0553

Email:       This email address is being protected from spambots. You need JavaScript enabled to view it.

 

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Seeking Consumer Representative for Gout Study (20/05/2016)

Researchers from the University of New South Wales are seeking consumer representatives to provide their ongoing perspectives and opinions on the planning, design, processes and proposed implementation of a study using technology to manage gout. We believe it is important to involve consumers and the community in our research.

We are looking for people who: 
 
• Have been diagnosed with gout by their GP.
• Are available to attend regular meetings (approx. 6-monthly across 2 years) held during working hours, on 
weekdays, either at St Vincent’s Hospital Sydney or Macquarie University. 

Click here for more details 
 

For further information please contact:

Contact: Dr Lauren Frensham

Phone: (02) 8382 2199

Email:  This email address is being protected from spambots. You need JavaScript enabled to view it.  

 

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Help needed for online Pain Research Survey (29/09/2015)

This is a brief online survey to help close the gap in our understanding of pain. 

You are likely eligible if you over 18 and suffer from rheumatoid arthritis, fibromyalgia, migraines, neck pain, whiplash or low back pain (will take only 15-minutes). If you have no current pain or history of persistent pain (a pain problem that lasted more than 3 months) then you are also eligible to take the survey as a control subject (takes 5-minutes only). 

Please follow this link to the survey: https://prodsurvey.rcs.griffith.edu.au/prodls190/index.php?sid=29267&lang=en

For more information contact Daniel at Griffith University:

Email:  This email address is being protected from spambots. You need JavaScript enabled to view it.
 

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Rheumatoid Arthritis: Make It A Family Affair (21/5/15)

The University of Queensland’s Diamantina Institute is investigating the prevention of rheumatoid arthritis before symptom onset.

Did you know that if you have rheumatoid arthritis, your family could be at greater risk of developing the disease at some point in their life?

Help them better understand how to prevent the development of rheumatoid arthritis in your loved ones by taking part in this study

Study participants need to be located in Brisbane and can be:

·      Rheumatoid arthritis patients  

·      Their first degree relatives

·      Healthy adults without rheumatoid arthritis

For more information, click here or contact Amelie:

Email:   This email address is being protected from spambots. You need JavaScript enabled to view it.  

Phone:  (07) 3443 6992    

 

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Internet-based Hip OsteoArthritis Pain Exacerbation (iHOAP) Study (26/03/15)

Do you have hip osteoarthritis diagnosed on an x-rayand have access to that x-ray?

Are you over 40 years old?

Do you experience hip pain on most days that fluctuates?

If so, you are invited to take part in an online study to help researchers determine the factors that influence your level of hip pain (e.g. weather, physical activity, foot-wear, hip injury, etc.).

For further information click here or to register visit www.ihoapstudy.info.

    

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FREE treatment to improve wellbeing for people 65 years or over with arthritis  (22/08/14)

The University of Sydney and beyondblue are jointly conducting a study aimed at all persons aged 65 years and over.

We are interested in how chronic illnesses, such as arthritis, affect older adults’ wellbeing. Persons who report at least one chronic illness may be eligible for the chance to receive 10 FREE sessions of psychological therapy with a registered psychologist, or a FREE online course to maintain wellbeing.

All persons aged 65 years or over are eligible to complete a 5-minute survey. Click here to complete the questionnaire.

Or contact Lauren Roche for a paper version of the survey:

Email:  This email address is being protected from spambots. You need JavaScript enabled to view it.

Phone: 02 9351 4257
    

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Do you have painful osteoarthritis in your knees? (9/4/14)

Some people with arthritis have great difficulty controlling their pain with usual medications. This may be because their pain is different. This study is investigating whether a different type of medication may be more effective for these people.

Researchers from Curtin University and Royal Perth Hospital are looking for volunteers to participate in a 4-week study, investigating the effects of a neuropathic pain medication on pain sensitivity, movement and quality of life in people with painful osteoarthritis of the knee. It would involve you taking pills for 28 days and attending 3 sessions for sensory and physical tests.

 NOTE: Study is being undertaken only in PERTH, WA.


For more details click here or

Email: Lisa Webster 
This email address is being protected from spambots. You need JavaScript enabled to view it.
 

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Research study to investigate how the brain effects the way muscles around the knee work  (05/03/14)

If you have been diagnosed with knee osteoarthritis, you are invited to participate in a study to investigate how the brain effects the way muscles around the knee work.

All procedures are non-invasive and pain-free and conducted at University of Western Sydney, Campbelltown campus.

For more information about the study click here or contact Abrahao Baptista at  This email address is being protected from spambots. You need JavaScript enabled to view it.  
 

 
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Personality style and Arthritis on overall health and wellbeing   (03/03/14)

If you have been diagnosed with Rheumatoid Arthritis or Osteoarthritis, you are invited to participate in a study designed to investigate the combined impact of personality and chronic illness on general health and functioning. The study involves completion of a online survey, with questions relating to symptoms, social support, health behaviour and personality. To access the survey directly, visit  https://www.deakin.edu.au/psychology/research/clinical_study.  


For more information click here or

Email: Sharon Horwood or Daniel at  This email address is being protected from spambots. You need JavaScript enabled to view it.  
 

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Low back pain PREVENT study - Participants needed   (03/02/14)

Are you currently suffering an acute (less than 4 weeks) episode of low back pain?

You are invited to participate in an NHMRC research project – the PREVENT study - which aims to help people recover early from their low back pain.

To participate, you will meet with a pain clinician at Neuroscience Research Australia (NeuRA), Barker Street, Randwick 2031, for an examination and two one-hour consultations. This service is completely free to you.


For more information click here or

Contact: Dr Markus Huebscher

T: 02 9399 1049

E:  This email address is being protected from spambots. You need JavaScript enabled to view it.    
 

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Seeking Consumer Representative for Gout Study (20/05/2016)

Researchers from the University of New South Wales are seeking consumer representatives to provide their ongoing perspectives and opinions on the planning, design, processes and proposed implementation of a study using technology to manage gout. We believe it is important to involve consumers and the community in our research.

 
We are looking for people who: 
 
• Have been diagnosed with gout by their GP.
• Are available to attend regular meetings (approx. 6-monthly across 2 years) held during working hours, on 
weekdays, either at St Vincent’s Hospital Sydney or Macquarie University. 

Click here for more details 
 
For further information please contact:

 

Phone: (02) 9385 6222

Email:  This email address is being protected from spambots. You need JavaScript enabled to view it.  

 

 

Do you suffer painful knee osteoarthritis? (28/07/14)

Specialists from Royal North Shore Hospital, St Leonards are conducting a six month research study that will observe whether different types of hyaluronic acid/steroid combination knee injection therapies can reduce pain severity in knee osteoarthritis patients.

You may be eligible if you are: between 40 and 85 years old, have mild to moderate knee pain due to osteoarthritis and taking pain mediation on most days.

All participants will receive one of three potential treatments: our investigational products, hyaluronic acid or steroid combination, or a frequently used product for management of knee osteoarthritis.

Participants will be reimbursed for travel and some out of pocket study related expenses.

For further detail  click here.

For details of other participating sites in Australia, click here.

Or further information contact:

Email: Tanya Fedorova  This email address is being protected from spambots. You need JavaScript enabled to view it.  or

Phone: 02 9463 1774

 

 

Are you living with an ongoing upper limb condition that affects your sex life?  (06/11/2015)

 

A satisfying sex life is important for well-being and quality of life. Ongoing upper limb conditions can have a profound effect on participation in sexual activities. However, sexual concerns are often ignored by health care professionals due to lack of knowledge. This study at Charles Sturt University aims to gain an insight into how upper limb conditions impact couples’ sex lives, how they adapt to any difficulties, and what type of information or assistance they want from health care professionals. A final outcome of the project will be the compilation of a fact sheet about upper limb conditions and sexual activity, which could be useful to both health care professionals and other people with ongoing upper limb conditions.

Participants should be:
  • over 18 years old
  • currently in a sexual relationship
  • have an ongoing upper limb condition/s 

Participants would also need to be prepared to be interviewed about their experiences.

For more information click here or contact Miranda Schroeder on: 

Phone: 02 6051 9225

Email:  This email address is being protected from spambots. You need JavaScript enabled to view it.

 

 

Melbourne OAKS - Osteoarthritis of the Knee Statin Study (25/5/2015)

The OAKS study is a randomised clinical trial, investigating a new treatment for knee osteoarthritis. It will compare statin tablets with an inactive placebo, looking at knee-cartilage-loss and other symptoms in people with knee pain. If statins are effective, they will offer a new way to slow the progression of knee osteoarthritis.

Participants should:

  • Have knee pain

  • Be 40-70 years old

  • Not currently be taking statins

For more information click here or contact Cameron, Molly, or Clare:

Phone:    03 9903 0553

Email:      This email address is being protected from spambots. You need JavaScript enabled to view it.

 
 

IMPACT persistent knee pain (25/03/14)

Are you over 50 years of age?

Have you had persistent knee pain on most days for 3 months?

Do you have access to an email account and broadband internet?

If so, you may be eligible to participate in a research project, the IMPACT trial conducted by the Department of Physiotherapy at The University of Melbourne that looks at different treatment options (such as online educational handouts, exercises delivered by a physiotherapist over the internet and online pain coping skills training) for people over 50 years of age with persistent knee pain to find out which one works best and why.

This is a nation-wide study and applies to people living all regions of Australia, including rural and remote areas 

If you are interested, please contact


Rachel Nelligan

Email:  This email address is being protected from spambots. You need JavaScript enabled to view it.

Or visit: http://chesm.unimelb.edu.au/volunteer/impact/impact.html

 

 

HOPE trial: Physiotherapy and education for people with persistent hip pain (25/03/14)

Are you over 50 years of age?

Have you had persistent hip pain, on most days for 3 months or more?

Do you have access to an email account and broadband internet?

Do you live in Victoria or Queensland?

If so, you may be eligible to participate in a research project, the HOPE trial which will compare different treatment options for people over 50 years of age with persistent hip pain to find out which one works best and why. If you decide to participate you will be randomly allocated to one of two groups. Each group will receive five physiotherapy exercise sessions and a home exercise program, and in addition will have access to two different forms of education online.

If you are interested, please contact


Rachel Nelligan

Email:  This email address is being protected from spambots. You need JavaScript enabled to view it.

Or visit: http://chesm.unimelb.edu.au/volunteer/hope/index.html

 

A trial assessing specifically modified shoes for those with knee osteoarthritis (25/10/13) Closed

The University of Melbourne's Department of Physiotherapy require participants over the age of 50, have had pain in their knee for more than three months and for most days of the past month and, be willing to wear walking shoes every day for six months.

If you think this sounds like you and would like more information on the project and participant eligibility, click here.

 

A study of risk factors for pain exacerbation in osteoarthritis of the knee (6/8/13) Closed

Sydney and Melbourne Universities are currently recruiting participants for the web based study of knee osteoarthritis pain.

For more information about the study, click here.

To express your interest register on the website www.chesm.unimelb.edu.au/volunteer/spark/spark.html

 

Associations between gender, coping and disability for people with chronic pain (2/7/13) Closed

This study examines whether or not gender influences what kind of coping strategies we use when living with chronic pain, and do these choices relate to how much disability we experience in everyday living. 

For the full details of this clinical trial, click here.

Please be advise that the closing date of this study is the 20th October.
 

 

New Zealand Green Lipped Mussel may improve symptoms of knee osteoarthritis (11/6/13) Closed

This is a research study of GlycOmega Plus™, a natural medicine made from New Zealand Green Lipped mussel.

GlycOmega Plus™ is currently available for purchase, and has been shown in previous trials to significantly improve knee pain, stiffness and joint mobility, as well as improve gastrointestinal function (primarily reflux, abdominal pain, bloating, flatulence, constipation and diarrhoea) in people with osteoarthritis of the knee.

For the full details of this clinical trial, please click
 here.

 

The Pain Course - An Internet-Delivered Education Program for the Management of Chronic Pain and Emotional Wellbeing (3/4/13) Closed


The Pain Course is a new internet-based course, which provides good information about chronic pain and teaches proven skills for managing chronic pain and emotional wellbeing. The aim of this course is to help people maintain good emotional wellbeing despite pain.

To find out more about the course click
 here.

 

A Clinical Research Opportunity for People with GOUT FLARES (14/1/13) Closed

Have you or a loved one tried everything for gout, but haven’t had any improvement in your symptoms? A local clinical research study is examining an investigational gout medication that’s designed to work differently from most other drugs.

If you're interested in exploring this option for gout, please click here.

 

Free online treatment program for people with Osteoarthritis suffering from depression (25/02/14) - Closed 12/01/15


The Clinical Research Unit for Anxiety and Depression (CRUfAD) is a joint facility of the University of New South Wales and St Vincent’s Hospital in Sydney Australia. CRUfAD provides face-to-face and internet treatment for people with anxiety and depressive disorders. The extensive team of researchers and clinicians within CRUfAD also conduct a range of epidemiological and treatment studies.


CRUfAD is currently recruiting for a study to evaluate an online treatment for depression in individuals withosteoarthritis.

This is a free 10 week program involving 6 lessons of cognitive behavioural therapy (CBT) delivered via the internet. CBT emphasises the relationship between thoughts, feelings and behaviours in creating change. The internet CBT course that we offer has been developed from a large amount of research which indicates that
CBT is effective in treating depression.

For more information and to determine if you are eligible to participate in this program, please visit https://trial.virtualclinic.org.au/homepage/apply

For moreinformation regarding the study, please click here. 

 

Painkiller Questionnaire - University of Derb(30/4/2014) Closed

The University of Derby is conducting a survey of pain and painkiller use in the USA, Canada, Australia and New Zealand. The survey has previously been conducted in the UK and is being extended to these countries in order to expand understanding of painkiller use.

Taking part will involve answering an online questionnaire which should take approximately 15-20 minutes.

To thank participants for their time, they will have the opportunity to enter a prize draw for Amazon vouchers worth $100.

If you would like to take part, or would like more information, click here.

 

Knee Brace Study (13/12/12) Closed

Seeking volunteers who have had an ACL reconstruction 

If you are between the ages of 23 and 50 years, have had an anterior cruciate ligament (ACL) reconstruction 5-20 years ago and would like to know more about this study click here 

 

Do you suffer from Rheumatoid Arthritis? (13/11/12) Closed

If your answer is yes and you would like to participate in an online study exploring how illness might alter our thoughts, feelings and behaviour, please read on by clicking here.
 

Do you have osteoarthritis of the knee and are over 40 years of age? (10/12) Closed

If you have answered yes, you may qualify for a research study of a lifestyle program to reduce knee pain and progression of arthritis.

For more information about the study click here.



Chronic Illness Research Project (17/8/11) Closed

Deakin University is conducting a study aimed at developing a questionnaire to assist in the diagnosis and assessment of treatment progression in chronic illness - specifically myalgic encephalomyelitis/chronic fatigue syndrome, fibromyalgia, and rheumatoid arthritis. If you have any of the following and are over 18 years of age, you might want to consider participating in the on-line questionnaire.

* Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

* Fibromyalgia

* Rheumatoid Arthritis

Click on the links below for the plain language statement with additional information about the study

About the study 
Plain language statement or visit www.deakin.edu.au/psychology/research/ci/



Brain structure and function in individuals with knee osteoarthritis (13/4/11) Closed

There is currently no cure or ideal treatment for knee osteoarthritis. People with knee osteoarthritis often experience pain, muscle weakness, joint stiffness and impaired sensation that can alter the way they walk and move.

Volunteering your time to this study will contribute to understanding the effect of knee osteoarthritis on the brain.

For information on how you can participate click here.

 

Telephone Coaching for Knee Osteoarthritis (20/06/12) Closed

The Universitiy of Melbourne's Department of Physiotherapy require participants over the age of 50, have had pain in their knee for more than three months and for most days of the past month and, can participate in a study for 18 months.

If you think this sounds like you and would like more information on the project and participant eligibility, click here.

 

The relative effectiveness of chronic pain management strategies used by adult community members (11/6/13) Closed

This study is investigating pain management strategies used by adults with chronic pain who live in the community. The study plans to consider how often these strategies are used and how effective they are in helping participants cope with their pain. 

For the full details of this clinical trial, please click here.

To go directly to the survey click here.


Motherhood Choices: A Decision Aid for Women with Rheumatoid Arthritis (6/13) Closed

Are you a women diagnosed with RA, aged between 20-45 and who may be contemplating pregnancy. We are seeking your help to recruit female patients to this trial. For more information click here.


Chronic Pain Study (16/05/12) Closed

Have you had intermittent or consistent pain or discomfort for the past three months?
If your answer is yes and you would like to participate in a study looking at emotional aspects of pain please read on by clicking
here.



Rheumatoid Arthritis Clinical Trial (updated 20 June, 2012) Closed

We are currently recruiting patients with active RA for participation in an international clinical trial with a new fully humanised IL-6 receptor antagonist.
The patient must have an inadequate clinical response to MTX defined as the presence of sufficient residual disease activity to meet eligibility criteria.


For more information and criteria
click here.


An Internet-Delivered Education Program for the Management of Chronic Pain and Emotional Wellbeing (14/11/11) Closed

Researchers from Macquarie University have developed a new internet-based education course (the Pain Course) designed to provide good information and practical skills for managing chronic pain, anxiety and depression. They have developed the course because Chronic Pain is common, but many people do not have access to good information about how to manage chronic pain and their emotional wellbeing. The aim of their research is to create a course that is practical, helpful, widely accessible and freely available to help people with Chronic Pain.

The course is supported with funding from the Motor Accidents Authority and consists of 5 online lessons available over 8 weeks. Simple summaries and tasks to help you learn the material will also be provided and a Clinical Psychologist will contact you each week to answer your questions, guide you through the course and monitor your progress. To participate in the course you must have chronic pain, but will also be experiencing symptoms of anxiety or low mood, be at least 18 years of age and living in Australia. To find out more about the course please visit
www.ecentreclinic.org and contact Dr Blake Dear at the contact@ecentreclinic.org To find out more about the course click here.



Exercise and Pain Coping Skills for knee osteoarthritis (14/6/11) Closed

Knee osteoarthritis can cause pain, stiffness and weakness. However, many people also report issues such as difficulty coping with pain, anxiety and low mood. Volunteering your time to this research will help us investigate the effectiveness of pain coping skills training and strengthening exercises provided by physiotherapists. You will be allocated to one of three treatment groups in Melbourne.

If you are aged over 50, have knee osteoarthritis and are interested in participating please click
here.


Knee Osteoarthritis and Neuromuscular Exercise (11/10/10)

The Universtiy of Melbourne's Department of Physiotherapy require participants over the age of 50, suffering from knee joint osteoarthritis for a research project to assist in the development of more effecitve treatment programs. Participants will be allocated to either a strengthening exercise treatment group or a neuromuscular exercise treatment group. For more information on the project and participant eligibility, click on the link below.

For more information click here.


Do you have hip arthritis? (3/6/10) Closed

The University of Melbourne's Department of Physiotherapy is seeking volunteers over the age of 50 who live in or near Melbourne, for a new research study that will evaluate the effectiveness of a physiotherapy program for people with pain from hip osteoarthritis. For an overview of the study and a complete summary, click on the links below.

Hip Osteoarthritis and Physiotherapy Study summary


Are you suffering from GOUT? (17/12/09) Closed

A clinical study is being conducted for patients with GOUT.  For more information, please click on the link below.

Click to download


Do you have Osteoarthritis in one or both knees? (2/7/08) Closed

Volunteers in the Illawarra region required:

Click to download

Wellbeing and chronic illness survey (19/02/09) (Closed)

Regardless of who we are or where we come from, few situations in life are as stressful as living with a chronic, physical illness. For more information about how your oppinion can assist us, please click on the link below.

 Click to download 

 

 

Reviewed and updated March 2016

 
 
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