Glucosamine and warfarin alert

Glucosamine is widely used for the symptoms of osteoarthritis. Recent reports have suggested that it may interact with warfarin and thus make blood less likely to clot. The mechanism for this is uncertain. However, Arthritis Australia recommends that patients on warfarin who are starting or stopping glucosamine should have their INR (blood clotting) checked regularly for the first month. Patients who are on stable doses of both are unlikely to have problems.

Prof. Graeme Jones
Arthritis Australia Medical Director

Reviewed and updated June 2012